7Y4Q

Semaphorin 6D in complex with Plexin A1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Plexin-A1	polymer	694	77079.1	2	UniProt (Q9UIW2) Pfam (PF01403) Pfam (PF01437) Pfam (PF17960)	Homo sapiens (human)	Semaphorin receptor NOV
2	C, D (D, C)	Semaphorin 6D	polymer	552	62522.6	2	UniProt (A0A0G2JZC4) Pfam (PF01403) Pfam (PF01437)	Rattus norvegicus (Norway rat)
3	E, F, G, H, I (F, H, E, G, I)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	5	In PDB GlyTouCan (G42666HT)
4	J, K, L, M (B, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)

Sequence modifications

B, A: 27 - 708 (UniProt: Q9UIW2)

PDB	External Database	Details
Gly 25	-	expression tag
Arg 26	-	expression tag
Ser 709	-	expression tag
Arg 710	-	expression tag
Leu 711	-	expression tag
Glu 712	-	expression tag
Asn 713	-	expression tag
Leu 714	-	expression tag
Tyr 715	-	expression tag
Phe 716	-	expression tag
Gln 717	-	expression tag
Gly 718	-	expression tag

D, C: 22 - 570 (UniProt: A0A0G2JZC4)

PDB	External Database	Details
Ser 19	-	expression tag
Ser 20	-	expression tag
Arg 21	-	expression tag
Gly 332	Ser 332	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	279203.5
Branched	Number of molecules	5
	Total formula weight	2122.0
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	282210.3

*Water molecules are not included.