7Y48

Cryo-EM Structure of biliverdin-bound mitochondrial ABC transporter ABCB10 from Biortus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	ATP-binding cassette sub-family B member 10, mitochondrial	polymer	613	67180.1	1	UniProt (Q9NRK6) Pfam (PF00664) Pfam (PF00005)	Homo sapiens (human)	ATP-binding cassette transporter 10,ABC transporter 10 protein
2	B (B)	CHOLESTEROL	non-polymer		386.7	1	Chemie (CLR)
3	C (B)	Biliverdine IX Alpha	non-polymer		582.6	1	Chemie (IE5)

Sequence modifications

B: 152 - 738 (UniProt: Q9NRK6)

PDB	External Database	Details
Met 151	-	initiating methionine
Gln 659	Glu 659	engineered mutation
Glu 739	-	expression tag
Asn 740	-	expression tag
Leu 741	-	expression tag
Tyr 742	-	expression tag
Phe 743	-	expression tag
Gln 744	-	expression tag
Gly 745	-	expression tag
Asp 746	-	expression tag
Tyr 747	-	expression tag
Lys 748	-	expression tag
Asp 749	-	expression tag
Asp 750	-	expression tag
Asp 751	-	expression tag
Asp 752	-	expression tag
Lys 753	-	expression tag
His 754	-	expression tag
His 755	-	expression tag
His 756	-	expression tag
His 757	-	expression tag
His 758	-	expression tag
His 759	-	expression tag
His 760	-	expression tag
His 761	-	expression tag
His 762	-	expression tag
His 763	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	67180.1
Non-Polymers*	Number of molecules	2
	Total formula weight	969.3
All*	Total formula weight	68149.4

*Water molecules are not included.