7Y28
Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional glutamate/proline--tRNA ligase | polymer | 497 | 56618.7 | 2 | UniProt (P07814) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) | Homo sapiens (human) | Bifunctional aminoacyl-tRNA synthetase,Cell proliferation-inducing gene 32 protein,Glutamatyl-prolyl-tRNA synthetase |
| 2 | C, H (A, B) | 1-[6-(3-fluorophenyl)benzimidazol-1-yl]-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one | non-polymer | 367.4 | 2 | Chemie (F96) | |||
| 3 | D, I (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 4 | E, J (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | F, G, K, L (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 113237.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1977.2 | |
| All* | Total formula weight | 115214.7 |
