7Y1R
Human L-TGF-beta1 in complex with the anchor protein LRRC33
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transforming growth factor beta-1 proprotein | polymer | 377 | 43010.4 | 2 | UniProt (P01137) Pfam (PF00688) Pfam (PF00019) | Homo sapiens (human) | |
| 2 | C (E) | Transforming growth factor beta activator LRRC33 | polymer | 656 | 72191.2 | 1 | UniProt (Q86YC3) Pfam (PF13855) | Homo sapiens (human) | Leucine-rich repeat-containing protein 33,Negative regulator of reactive oxygen species |
| 3 | D, G, H, I, J (L, F, G, H, I) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 5 | In PDB GlyTouCan (G15407YE) | |||
| 4 | E (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G79924RM) | |||
| 6 | K (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A, B: 1 - 361 (UniProt: P01137)
E: 1 - 631 (UniProt: Q86YC3)
| PDB | External Database | Details |
|---|---|---|
| Met -15 | - | initiating methionine |
| Pro -14 | - | expression tag |
| Leu -13 | - | expression tag |
| Leu -12 | - | expression tag |
| Leu -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Pro -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Trp -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -15 | - | initiating methionine |
| Pro -14 | - | expression tag |
| Leu -13 | - | expression tag |
| Leu -12 | - | expression tag |
| Leu -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Pro -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Trp -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ser 632 | - | expression tag |
| Asn 633 | - | expression tag |
| Ser 634 | - | expression tag |
| Leu 635 | - | expression tag |
| Glu 636 | - | expression tag |
| Val 637 | - | expression tag |
| Leu 638 | - | expression tag |
| Phe 639 | - | expression tag |
| Gln 640 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 158212.0 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 3781.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 162214.7 |
