7Y1H
Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bifunctional glutamate/proline--tRNA ligase | polymer | 512 | 58087.4 | 2 | UniProt (P07814) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) In PDB | Homo sapiens (human) | Bifunctional aminoacyl-tRNA synthetase,Cell proliferation-inducing gene 32 protein,Glutamatyl-prolyl-tRNA synthetase |
| 2 | A, B | 1-(5-chloranyl-4-methyl-benzimidazol-1-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one | non-polymer | 321.8 | 2 | Chemie (F99) | |||
| 3 | A, B | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 4 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | water | water | 18.0 | 201 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116174.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1886.0 | |
| All* | Total formula weight | 118060.8 |
