7XZR
Crystal structure of TNIK-AMPPNP-thiopeptide TP15 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | TRAF2 and NCK-interacting protein kinase | polymer | 306 | 35118.2 | 2 | UniProt (Q9UKE5) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | C, D (C, D) | thiopeptide TP15 | polymer | 18 | 1858.2 | 2 | BIRD (PRD_002381) | synthetic construct | |
| 3 | E, J (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 4 | F, K (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, H, L (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | I (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 7 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A, B: 11 - 314 (UniProt: Q9UKE5)
| PDB | External Database | Details |
|---|---|---|
| Gly 9 | - | expression tag |
| Pro 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 73952.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1499.4 | |
| All* | Total formula weight | 75452.1 |
