7XZH

Cryo-EM structure of human LRRC8A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Volume-regulated anion channel subunit LRRC8A	polymer	808	94119.3	6	UniProt (Q8IWT6) Pfam (PF12534) Pfam (PF13855) In PDB	Homo sapiens (human)	Leucine-rich repeat-containing protein 8A,HsLRRC8A,Swelling protein 1
2	F, A, B, C, D...	O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine	non-polymer		792.1	6	Chemie (P5S)
3	F, A, B, C, D...	(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate	non-polymer		760.1	6	Chemie (POV)
4	F, A, B, C, D...	CHOLESTEROL	non-polymer		386.7	12	Chemie (CLR)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	564715.9
Non-Polymers*	Number of molecules	24
	Total formula weight	13952.8
All*	Total formula weight	578668.6

*Water molecules are not included.