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7XZH

Cryo-EM structure of human LRRC8A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Volume-regulated anion channel subunit LRRC8Apolymer80894119.36UniProt (Q8IWT6)
Pfam (PF12534)
Pfam (PF13855)
Pfam (PF23598)
Homo sapiens (human)Leucine-rich repeat-containing protein 8A,HsLRRC8A,Swelling protein 1
2AA, G, M, Q, S...
(F, A, B, C, D...)
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serinenon-polymer792.16Chemie (P5S)
3BA, H, N, R, T...
(F, A, B, C, D...)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.16Chemie (POV)
4CA, DA, I, J, K...
(F, A, B, C, D...)
CHOLESTEROLnon-polymer386.712Chemie (CLR)
PubChem (5997)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight564715.9
Non-Polymers*Number of molecules24
Total formula weight13952.8
All*Total formula weight578668.6
*Water molecules are not included.

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PDB entries from 2026-05-27

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