7XXT
HapR Quadruple mutant, bound to IMTVC-212
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hemagglutinin/protease regulatory protein | polymer | 203 | 23648.3 | 1 | UniProt (B2CKP3) Pfam (PF00440) | Vibrio cholerae | TetR/AcrR family transcriptional regulator |
| 2 | B (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 3 | C (A) | 1-((5-phenylthiophen-2-yl)sulfonyl)-1H-pyrazole | non-polymer | 290.4 | 1 | Chemie (7PI) | |||
| 4 | D (A) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 1 - 203 (UniProt: B2CKP3)
| PDB | External Database | Details |
|---|---|---|
| Phe 76 | Tyr 76 | engineered mutation |
| Ile 97 | Leu 97 | engineered mutation |
| Val 141 | Ile 141 | engineered mutation |
| Cys 171 | Phe 171 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23648.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 368.5 | |
| All* | Total formula weight | 24016.8 |
