7XWN
structure of patulin-detoxifying enzyme Y155F/V187K with NADPH and substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Short-chain dehydrogenase/reductase | polymer | 250 | 27387.1 | 4 | UniProt (A0A888VSF1) Pfam (PF13561) | Meyerozyma guilliermondii | |
| 2 | E, F, G, I (A, B, C, D) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 4 | Chemie (NDP) | |||
| 3 | H (C) | (4~{S})-4-oxidanyl-4,6-dihydrofuro[3,2-c]pyran-2-one | non-polymer | 154.1 | 1 | Chemie (I8L) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 602 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 250 (UniProt: A0A888VSF1)
| PDB | External Database | Details |
|---|---|---|
| Phe 155 | Tyr 155 | engineered mutation |
| Lys 187 | Val 187 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 109548.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 3135.8 | |
| All* | Total formula weight | 112684.3 |
