7XVN

Structural basis for DNA recognition feature of retinoid-related orphan receptors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Nuclear receptor ROR-gamma	polymer	123	13865.0	4	UniProt (P51450) Pfam (PF00105) In PDB	Mus musculus (house mouse)	Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma,Thymus orphan receptor,TOR
2	N, E	DNA (5'-D(P*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3')	polymer	18	5460.6	2		Homo sapiens
3	P, F	DNA (5'-D(P*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3')	polymer	18	5571.6	2		Homo sapiens
4	A, B, C, D	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
5		water	water		18.0	119	Chemie (HOH)

Sequence modifications

A, B, C, D: 24 - 117 (UniProt: P51450)

PDB	External Database	Details
Met -5	-	initiating methionine
Gly -4	-	expression tag
Ser -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
Ser 5	-	expression tag
Ser 6	-	expression tag
Gly 7	-	expression tag
Leu 8	-	expression tag
Val 9	-	expression tag
Pro 10	-	expression tag
Arg 11	-	expression tag
Gly 12	-	expression tag
Ser 13	-	expression tag
His 14	-	expression tag
Met 15	-	expression tag
Leu 16	-	expression tag
Glu 17	-	expression tag
Val 18	-	expression tag
Leu 19	-	expression tag
Phe 20	-	expression tag
Gln 21	-	expression tag
Gly 22	-	expression tag
Pro 23	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	77524.2
Non-Polymers*	Number of molecules	8
	Total formula weight	523.3
All*	Total formula weight	78047.5

*Water molecules are not included.