7XU3
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Closed Conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, A, C) | Spike glycoprotein | polymer | 1127 | 124727.2 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 2 | D, E, F, G, H... (K, M, P, a, c...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 3 | GA, M, W (C, B, A) | BILIVERDINE IX ALPHA | non-polymer | 582.6 | 3 | Chemie (BLA) | |||
| 4 | AA, BA, CA, DA, EA... (A, C, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 27 | Chemie (NAG) |
Sequence modifications
B, A, C: 14 - 1140 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Glu 10 | - | expression tag |
| Thr 11 | - | expression tag |
| Gly 12 | - | expression tag |
| Thr 13 | - | expression tag |
| Cys 427 | Asp 427 | engineered mutation |
| - | Pro 681 | deletion |
| - | Arg 682 | deletion |
| - | Arg 683 | deletion |
| - | Ala 684 | deletion |
| Cys 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 374181.7 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 3819.6 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 7720.6 | |
| All* | Total formula weight | 385721.9 |
