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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7XTI

RNA polymerase II elongation complex transcribing a nucleosome (EC58hex)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)		DNA-directed RNA polymerase subunitpolymer1743194107.41UniProt (C4R4Y0)
Pfam (PF04997)
Pfam (PF05001)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)		Komagataella phaffii
2B
(B)		DNA-directed RNA polymerase subunit betapolymer1227139746.11UniProt (C4QZQ7)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)		Komagataella phaffii
3C
(C)		RNA polymerase II third largest subunit B44, part of central corepolymer30434216.31UniProt (C4R7L2)
Pfam (PF01193)
Pfam (PF01000)		Komagataella phaffii
4D
(D)		RNA polymerase II subunit B32polymer18620623.01UniProt (C4R2U9)
Pfam (PF03874)		Komagataella phaffii
5E
(E)		DNA-directed RNA polymerases I, II, and III subunit RPABC1polymer21424962.71UniProt (C4R3P8)
Pfam (PF03871)
Pfam (PF01191)		Komagataella phaffii
6F
(F)		RNA polymerase subunit ABC23, common to RNA polymerases I, II, and IIIpolymer15517803.61UniProt (C4R1V1)
Pfam (PF01192)		Komagataella phaffii
7G
(G)		RNA polymerase II subunitpolymer17118802.61UniProt (C4R9A1)
Pfam (PF03876)
Pfam (PF00575)		Komagataella phaffii
8H
(H)		DNA-directed RNA polymerases I, II, and III subunit RPABC3polymer14516249.21UniProt (C4R273)
Pfam (PF03870)		Komagataella phaffii
9I
(I)		DNA-directed RNA polymerase subunitpolymer11513612.31UniProt (F2QPE6)
Pfam (PF02150)
Pfam (PF01096)		Komagataella phaffii
10J
(J)		RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and IIIpolymer728554.11UniProt (C4R009)
Pfam (PF01194)		Komagataella phaffii
11K
(K)		RNA polymerase II subunit B12.5polymer11813832.91UniProt (C4R3Z5)
Pfam (PF13656)		Komagataella phaffii
12L
(L)		RNA polymerase subunit ABC10-alphapolymer727862.01UniProt (F2QMI1)
Pfam (PF03604)		Komagataella phaffii
13M
(M)		Transcription elongation factor 1 homologpolymer11312606.91UniProt (C4QZ45)
Pfam (PF05129)		Komagataella phaffii
14N
(N)		DNA (198-MER)polymer19861381.91synthetic construct
15O
(P)		RNA (5'-R(P*UP*GP*UP*AP*AP*UP*CP*CP*CP*CP*UP*UP*GP*GP*CP*GP*GP*UP*U)-3')polymer196008.61synthetic construct
16P
(T)		DNA (198-MER)polymer19860870.01synthetic construct
17Q
(V)		Transcription elongation factor SPT4polymer10812039.61UniProt (C4R0E6)
Pfam (PF06093)		Komagataella phaffii
18R
(W)		Transcription elongation factor SPT5polymer911101459.41UniProt (C4R370)
Pfam (PF11942)
Pfam (PF03439)
Pfam (PF00467)
Pfam (PF12815)		Komagataella phaffiiChromatin Elongation factor SPT5,Transcription elongation factor spt5
19S
(m)		Transcription elongation factor Spt6polymer1503173241.61UniProt (C4R7H2)
Pfam (PF14632)
Pfam (PF14641)
Pfam (PF22706)
Pfam (PF14639)
Pfam (PF14635)
Pfam (PF21710)
Pfam (PF14633)		Komagataella phaffii
20T
(n)		Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase IIpolymer41746907.81UniProt (C4R7L8)
Pfam (PF08711)		Komagataella phaffii
21U
(q)		Component of the Paf1p complexpolymer1084124979.01UniProt (C4R6B2)
Pfam (PF13432)		Komagataella phaffii
22V
(r)		RNAPII-associated chromatin remodeling Paf1 complex subunitpolymer54462301.21UniProt (F2QQ42)
Pfam (PF03126)		Komagataella phaffii
23W
(u)		Leo1polymer45952387.71UniProt (C4R3K1)
Pfam (PF04004)		Komagataella phaffii
24X
(v)		RNAP II-associated proteinpolymer39646046.01UniProt (C4R997)
Pfam (PF03985)		Komagataella phaffii
25Y
(x)		Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4ppolymer39544760.71UniProt (C4R1E6)
Pfam (PF05179)		Komagataella phaffii
26BA, Z
(a, e)		Histone H3.3polymer13915643.32UniProt (P84243)
Pfam (PF00125)		Homo sapiens (human)
27AA, CA
(b, f)		Histone H4polymer10611676.72UniProt (P62805)
Pfam (PF15511)		Homo sapiens (human)
28DA
(g)		Histone H2A type 1-B/Epolymer13314447.81UniProt (P04908)
Pfam (PF00125)
Pfam (PF16211)		Homo sapiens (human)Histone H2A.2,Histone H2A/a,Histone H2A/m
29EA
(h)		Histone H2B type 1-Jpolymer12914217.51UniProt (P06899)
Pfam (PF00125)		Homo sapiens (human)Histone H2B.1,Histone H2B.r,H2B/r
30FA
(j)		FACT complex subunitpolymer1008115220.71UniProt (C4QYQ8)
Pfam (PF14826)
Pfam (PF00557)
Pfam (PF08644)
Pfam (PF08512)		Komagataella phaffii
31GA
(k)		FACT complex subunit POB3polymer53160292.31UniProt (F2QNN8)
Pfam (PF17292)
Pfam (PF03531)
Pfam (PF21103)
Pfam (PF08512)		Komagataella phaffii
32HA, IA, KA, LA, MA...
(A, B, C, I, J...)		ZINC IONnon-polymer65.410Chemie (ZN)
33JA
(A)		MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence modifications
M: 1 - 110 (UniProt: C4QZ45)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Gly 0-expression tag
V: 8 - 114 (UniProt: C4R0E6)
PDBExternal DatabaseDetails
Met 7-initiating methionine
W: 1 - 908 (UniProt: C4R370)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Gly 0-expression tag
m: 1 - 1500 (UniProt: C4R7H2)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Gly 0-expression tag
n: 1 - 414 (UniProt: C4R7L8)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Gly 0-expression tag
q: 1 - 1044 (UniProt: C4R6B2)
PDBExternal DatabaseDetails
Met -39-initiating methionine
Lys -38-expression tag
Asp -37-expression tag
His -36-expression tag
Leu -35-expression tag
Ile -34-expression tag
His -33-expression tag
Asn -32-expression tag
His -31-expression tag
His -30-expression tag
Lys -29-expression tag
His -28-expression tag
Glu -27-expression tag
His -26-expression tag
Ala -25-expression tag
His -24-expression tag
Ala -23-expression tag
Glu -22-expression tag
His -21-expression tag
Asp -20-expression tag
Tyr -19-expression tag
Lys -18-expression tag
Asp -17-expression tag
Asp -16-expression tag
Asp -15-expression tag
Asp -14-expression tag
Lys -13-expression tag
Glu -12-expression tag
His -11-expression tag
Leu -10-expression tag
Tyr -9-expression tag
Phe -8-expression tag
Gln -7-expression tag
Gly -6-expression tag
Ser -5-expression tag
Ser -4-expression tag
Gly -3-expression tag
Ser -2-expression tag
Ser -1-expression tag
Gly 0-expression tag
r: 1 - 514 (UniProt: F2QQ42)
PDBExternal DatabaseDetails
Met -29-initiating methionine
Lys -28-expression tag
Asp -27-expression tag
His -26-expression tag
Leu -25-expression tag
Ile -24-expression tag
His -23-expression tag
Asn -22-expression tag
His -21-expression tag
His -20-expression tag
Lys -19-expression tag
His -18-expression tag
Glu -17-expression tag
His -16-expression tag
Ala -15-expression tag
His -14-expression tag
Ala -13-expression tag
Glu -12-expression tag
His -11-expression tag
Leu -10-expression tag
Tyr -9-expression tag
Phe -8-expression tag
Gln -7-expression tag
Gly -6-expression tag
Ser -5-expression tag
Ser -4-expression tag
Gly -3-expression tag
Ser -2-expression tag
Ser -1-expression tag
Gly 0-expression tag
u: 1 - 429 (UniProt: C4R3K1)
PDBExternal DatabaseDetails
Met -29-initiating methionine
Lys -28-expression tag
Asp -27-expression tag
His -26-expression tag
Leu -25-expression tag
Ile -24-expression tag
His -23-expression tag
Asn -22-expression tag
His -21-expression tag
His -20-expression tag
Lys -19-expression tag
His -18-expression tag
Glu -17-expression tag
His -16-expression tag
Ala -15-expression tag
His -14-expression tag
Ala -13-expression tag
Glu -12-expression tag
His -11-expression tag
Leu -10-expression tag
Tyr -9-expression tag
Phe -8-expression tag
Gln -7-expression tag
Gly -6-expression tag
Ser -5-expression tag
Ser -4-expression tag
Gly -3-expression tag
Ser -2-expression tag
Ser -1-expression tag
Gly 0-expression tag
v: 1 - 393 (UniProt: C4R997)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
Ala 0-expression tag
x: 1 - 365 (UniProt: C4R1E6)
PDBExternal DatabaseDetails
Met -29-initiating methionine
Lys -28-expression tag
Asp -27-expression tag
His -26-expression tag
Leu -25-expression tag
Ile -24-expression tag
His -23-expression tag
Asn -22-expression tag
His -21-expression tag
His -20-expression tag
Lys -19-expression tag
His -18-expression tag
Glu -17-expression tag
His -16-expression tag
Ala -15-expression tag
His -14-expression tag
Ala -13-expression tag
Glu -12-expression tag
His -11-expression tag
Leu -10-expression tag
Tyr -9-expression tag
Phe -8-expression tag
Gln -7-expression tag
Gly -6-expression tag
Ser -5-expression tag
Ser -4-expression tag
Gly -3-expression tag
Ser -2-expression tag
Ser -1-expression tag
Gly 0-expression tag
a, e: 0 - 135 (UniProt: P84243)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ser -2-expression tag
His -1-expression tag
b, f: 0 - 102 (UniProt: P62805)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ser -2-expression tag
His -1-expression tag
g: 0 - 129 (UniProt: P04908)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ser -2-expression tag
His -1-expression tag
h: -3 - 122 (UniProt: P06899)
PDBExternal DatabaseDetails
Gly -6-expression tag
Ser -5-expression tag
His -4-expression tag
j: 1 - 1005 (UniProt: C4QYQ8)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Gly 0-expression tag
k: 1 - 528 (UniProt: F2QNN8)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains33
Total formula weight1574180.9
Non-Polymers*Number of molecules11
Total formula weight678.4
All*Total formula weight1574859.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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