7XSV
Crystal Structures of PIM1 in Complex with Macrocyclic Compound H3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Serine/threonine-protein kinase pim-1 | polymer | 289 | 33292.7 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (human) | |
2 | A | 8-Methyl-2,5,20-trioxa-8,13,17-triazatetracyclo[11.10.2.014,19.021,25]pentacosa-1(24),14(19),15,17,21(25),22-hexaene | non-polymer | 355.4 | 1 | Chemie (I4M) | |||
3 | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A: 29 - 313 (UniProt: P11309)
PDB | External Database | Details |
---|---|---|
Gly 25 | - | expression tag |
Pro 26 | - | expression tag |
His 27 | - | expression tag |
Met 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33292.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 355.4 | |
All* | Total formula weight | 33648.1 |