7XSC

Crystal structure of SARS-CoV-2 spike receptor binding domain bound with P5S-2B10

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, D)	P5S-2B10 Heavy chain	polymer	220	23273.0	2		Homo sapiens (human)
2	C, D (E, F)	Spike protein S1	polymer	258	28969.7	2	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
3	E, F (B, H)	P5S-2B10 Light chain	polymer	214	23432.0	2		Homo sapiens (human)

Sequence modifications

E, F: 319 - 529 (UniProt: P0DTC2)

PDB	External Database	Details
Met 278	-	initiating methionine
Leu 279	-	expression tag
Leu 280	-	expression tag
Val 281	-	expression tag
Asn 282	-	expression tag
Gln 283	-	expression tag
Ser 284	-	expression tag
His 285	-	expression tag
Gln 286	-	expression tag
Gly 287	-	expression tag
Phe 288	-	expression tag
Asn 289	-	expression tag
Lys 290	-	expression tag
Glu 291	-	expression tag
His 292	-	expression tag
Thr 293	-	expression tag
Ser 294	-	expression tag
Lys 295	-	expression tag
Met 296	-	expression tag
Val 297	-	expression tag
Ser 298	-	expression tag
Ala 299	-	expression tag
Ile 300	-	expression tag
Val 301	-	expression tag
Leu 302	-	expression tag
Tyr 303	-	expression tag
Val 304	-	expression tag
Leu 305	-	expression tag
Leu 306	-	expression tag
Ala 307	-	expression tag
Ala 308	-	expression tag
Ala 309	-	expression tag
Ala 310	-	expression tag
His 311	-	expression tag
Ser 312	-	expression tag
Ala 313	-	expression tag
Phe 314	-	expression tag
Ala 315	-	expression tag
Ala 316	-	expression tag
Asp 317	-	expression tag
Pro 318	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	151349.5
All*	Total formula weight	151349.5

*Water molecules are not included.