7XSB
Crystal structure of SARS-CoV-2 spike receptor binding domain bound with P5S-3B11 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (E, A, B, C) | Spike protein S1 | polymer | 243 | 27234.7 | 4 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 2 | E, G, I, K (H, D, G, J) | P5S-3B11 Heavy chain | polymer | 217 | 23307.2 | 4 | Homo sapiens | ||
| 3 | F, H, J, L (L, F, I, K) | P5S-3B11 Light chain | polymer | 216 | 23186.5 | 4 | Homo sapiens |
Sequence modifications
E, A, B, C: 333 - 528 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Met 292 | - | initiating methionine |
| Leu 293 | - | expression tag |
| Leu 294 | - | expression tag |
| Val 295 | - | expression tag |
| Asn 296 | - | expression tag |
| Gln 297 | - | expression tag |
| Ser 298 | - | expression tag |
| His 299 | - | expression tag |
| Gln 300 | - | expression tag |
| Gly 301 | - | expression tag |
| Phe 302 | - | expression tag |
| Asn 303 | - | expression tag |
| Lys 304 | - | expression tag |
| Glu 305 | - | expression tag |
| His 306 | - | expression tag |
| Thr 307 | - | expression tag |
| Ser 308 | - | expression tag |
| Lys 309 | - | expression tag |
| Met 310 | - | expression tag |
| Val 311 | - | expression tag |
| Ser 312 | - | expression tag |
| Ala 313 | - | expression tag |
| Ile 314 | - | expression tag |
| Val 315 | - | expression tag |
| Leu 316 | - | expression tag |
| Tyr 317 | - | expression tag |
| Val 318 | - | expression tag |
| Leu 319 | - | expression tag |
| Leu 320 | - | expression tag |
| Ala 321 | - | expression tag |
| Ala 322 | - | expression tag |
| Ala 323 | - | expression tag |
| Ala 324 | - | expression tag |
| His 325 | - | expression tag |
| Ser 326 | - | expression tag |
| Ala 327 | - | expression tag |
| Phe 328 | - | expression tag |
| Ala 329 | - | expression tag |
| Ala 330 | - | expression tag |
| Asp 331 | - | expression tag |
| Pro 332 | - | expression tag |
| Asn 417 | Lys 417 | variant |
| Lys 484 | Glu 484 | variant |
| Tyr 501 | Asn 501 | variant |
| His 529 | - | expression tag |
| His 530 | - | expression tag |
| His 531 | - | expression tag |
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 294913.6 | |
| All* | Total formula weight | 294913.6 |
