7XSA

Crystal structure of SARS-CoV-2 spike receptor binding domain bound with P2S-2E9 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (B, H)	P2S-2E9 Heavy chain	polymer	218	23451.6	2		Homo sapiens
2	B, E (C, I)	P2S-2E9 Light chain	polymer	215	22608.9	2		Homo sapiens
3	C, F (E, J)	Spike protein S1	polymer	242	27105.5	2	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)

Sequence modifications

E, J: 333 - 527 (UniProt: P0DTC2)

PDB	External Database	Details
Met 292	-	initiating methionine
Leu 293	-	expression tag
Leu 294	-	expression tag
Val 295	-	expression tag
Asn 296	-	expression tag
Gln 297	-	expression tag
Ser 298	-	expression tag
His 299	-	expression tag
Gln 300	-	expression tag
Gly 301	-	expression tag
Phe 302	-	expression tag
Asn 303	-	expression tag
Lys 304	-	expression tag
Glu 305	-	expression tag
His 306	-	expression tag
Thr 307	-	expression tag
Ser 308	-	expression tag
Lys 309	-	expression tag
Met 310	-	expression tag
Val 311	-	expression tag
Ser 312	-	expression tag
Ala 313	-	expression tag
Ile 314	-	expression tag
Val 315	-	expression tag
Leu 316	-	expression tag
Tyr 317	-	expression tag
Val 318	-	expression tag
Leu 319	-	expression tag
Leu 320	-	expression tag
Ala 321	-	expression tag
Ala 322	-	expression tag
Ala 323	-	expression tag
Ala 324	-	expression tag
His 325	-	expression tag
Ser 326	-	expression tag
Ala 327	-	expression tag
Phe 328	-	expression tag
Ala 329	-	expression tag
Ala 330	-	expression tag
Asp 331	-	expression tag
Pro 332	-	expression tag
Asn 417	Lys 417	variant
Lys 484	Glu 484	variant
Tyr 501	Asn 501	variant
His 528	-	expression tag
His 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	146331.9
All*	Total formula weight	146331.9

*Water molecules are not included.