7XQX
Crystal structure of T2R-TTL-27a complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1B chain | polymer | 450 | 50041.3 | 2 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) | Sus scrofa (pig) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B, D (B, D) | Tubulin beta chain | polymer | 445 | 49999.9 | 2 | UniProt (A0A287AGU7) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P02554) | Sus scrofa (pig) | |
| 3 | E (E) | Stathmin-4 | polymer | 143 | 16844.2 | 1 | UniProt (P63042) Pfam (PF00836) | Mus musculus (house mouse) | Stathmin-like protein B3,RB3 |
| 4 | F (F) | TTL | polymer | 384 | 44378.5 | 1 | UniProt (E1BQ43) | Gallus gallus (chicken) | |
| 5 | G, P (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 6 | H, L, Q (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) PubChem (888) | |||
| 7 | I, R (A, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 8 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 9 | K, S (B, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 10 | M, N (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) PubChem (4478249) | |||
| 11 | O, T (B, D) | 2-chloranyl-7-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine | non-polymer | 317.7 | 2 | Chemie (GXI) PubChem (168059286) |
Sequence modifications
E: 5 - 145 (UniProt: P63042)
F: 1 - 378 (UniProt: E1BQ43)
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| Ala 4 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| His 379 | - | expression tag |
| His 380 | - | expression tag |
| His 381 | - | expression tag |
| His 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 261305.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3147.3 | |
| All* | Total formula weight | 264452.2 |
