7XQD

Structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE/CHS nanodiscs (C1 symmetry)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Gap junction alpha-1 protein	polymer	257	29396.5	12	UniProt (P17302) Pfam (PF00029)	Homo sapiens (human)	Connexin-43,Cx43,Gap junction 43 kDa heart protein
2	AA, AB, AC, AD, AE... (B, D, F, H, J...)	TETRADECANE	non-polymer		198.4	108	Chemie (C14) PubChem (12389)
3	IA, IB, ID, IE, JC... (B, D, H, J, F...)	PHOSPHATIDYLETHANOLAMINE	non-polymer		734.0	24	Chemie (PTY) PubChem (446872) PubChem (3330137)
4	JA, JB, JD, JE, KA... (B, D, H, J, F...)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	24	Chemie (Y01) PubChem (65082) PubChem (363416) PubChem (500055) PubChem (13301926) PubChem (13301927) PubChem (16219150) PubChem (22210610) PubChem (45489984) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (155804219) PubChem (169132514) PubChem (60078761) PubChem (73440805) PubChem (99567469) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (124914595) PubChem (124914596) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028)
5	MF, NF, OF, PF, QF... (A, B, C, D, E...)	water	water		18.0	272	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	352758.6
Non-Polymers*	Number of molecules	156
	Total formula weight	50724.3
All*	Total formula weight	403482.8

*Water molecules are not included.