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7XQB

Structure of connexin43/Cx43/GJA1 gap junction intercellular channel in POPE/CHS nanodiscs at pH ~8.0

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, G, B, C, D...)
Gap junction alpha-1 proteinpolymer38243061.312UniProt (P17302)
Pfam (PF00029)
Pfam (PF03508)
Homo sapiens (human)Connexin-43,Cx43,Gap junction 43 kDa heart protein
2AA, AC, AD, AE, AF...
(G, D, F, I, K...)
TETRADECANEnon-polymer198.4132Chemie (C14)
3AB, BC, CC, ED, FA...
(B, D, F, G, I...)
CHOLESTEROL HEMISUCCINATEnon-polymer486.724Chemie (Y01)
4BB, DC, HA, HE, JF...
(B, D, G, I, K...)
PHOSPHATIDYLETHANOLAMINEnon-polymer734.012Chemie (PTY)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight516736.0
Non-Polymers*Number of molecules168
Total formula weight46677.1
All*Total formula weight563413.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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