7XQ1

Structure of hSLC19A1+2'3'-CDAS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Reduced folate transporter	polymer	544	60556.1	1	UniProt (P41440) Pfam (PF01770)	Homo sapiens (human)	FOLT,Intestinal folate carrier 1,IFC-1,Placental folate transporter,Reduced folate carrier protein,RFC,hRFC,Reduced folate transporter 1,RFT-1,Solute carrier family 19 member 1,hSLC19A1
2	B, C (A)	(1~{R},3~{S},6~{R},8~{R},9~{R},10~{S},12~{S},15~{R},17~{R},18~{R})-8,17-bis(6-aminopurin-9-yl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecane-9,18-diol	non-polymer		690.5	2	Chemie (GJF)

Sequence modifications

A: 1 - 506 (UniProt: P41440)

PDB	External Database	Details
Met -2	-	initiating methionine
Gly -1	-	expression tag
Ser 0	-	expression tag
Lys 507	-	expression tag
Leu 508	-	expression tag
Gly 509	-	expression tag
Ser 510	-	expression tag
Glu 511	-	expression tag
Asn 512	-	expression tag
Leu 513	-	expression tag
Tyr 514	-	expression tag
Leu 515	-	expression tag
Glu 516	-	expression tag
Val 517	-	expression tag
Leu 518	-	expression tag
Phe 519	-	expression tag
Gln 520	-	expression tag
Gly 521	-	expression tag
Pro 522	-	expression tag
Phe 523	-	expression tag
Gln 524	-	expression tag
Gly 525	-	expression tag
Gly 526	-	expression tag
Ser 527	-	expression tag
Gly 528	-	expression tag
Gly 529	-	expression tag
Ser 530	-	expression tag
Gly 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	60556.1
Non-Polymers*	Number of molecules	2
	Total formula weight	1381.1
All*	Total formula weight	61937.2

*Water molecules are not included.