7XOW
Structural insights into human brain gut peptide cholecystokinin receptors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Gastrin/cholecystokinin type B receptor | polymer | 447 | 48470.0 | 1 | UniProt (P32239) Pfam (PF00001) | Homo sapiens (human) | CCK-B receptor,CCK-BR,Cholecystokinin-2 receptor,CCK2-R |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37915.5 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 70 | 7729.9 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (E) | scfv16 | polymer | 269 | 28813.0 | 1 | Mus musculus | ||
| 5 | E (A) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 353 | 41238.9 | 1 | UniProt (P50148) Pfam (PF00503) UniProt (by SIFTS) (P63096) | Homo sapiens (human) | Guanine nucleotide-binding protein alpha-q |
| 6 | F (L) | Gastrin | polymer | 17 | 2197.3 | 1 | UniProt (P01350) Pfam (PF00918) | Homo sapiens |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
A: 30 - 353 (UniProt: P50148)
L: 1 - 17 (UniProt: P01350)
| PDB | External Database | Details |
|---|---|---|
| Met -4 | - | initiating methionine |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Gln 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 2 | - | expression tag |
| Cys 3 | - | expression tag |
| Thr 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Glu 8 | - | expression tag |
| Asp 9 | - | expression tag |
| Lys 10 | - | expression tag |
| Ala 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Val 13 | - | expression tag |
| Glu 14 | - | expression tag |
| Arg 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Lys 17 | - | expression tag |
| Met 18 | - | expression tag |
| Ile 19 | - | expression tag |
| Asp 20 | - | expression tag |
| Arg 21 | - | expression tag |
| Asn 22 | - | expression tag |
| Leu 23 | - | expression tag |
| Arg 24 | - | expression tag |
| Glu 25 | - | expression tag |
| Asp 26 | - | expression tag |
| Gly 27 | - | expression tag |
| Glu 28 | - | expression tag |
| Lys 29 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Glu 1 | Gln 76 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 166364.6 | |
| All* | Total formula weight | 166364.6 |
