7XNL
human KCNQ1-CaM-ML277-PIP2 complex in state A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Potassium voltage-gated channel subfamily KQT member 1 | polymer | 692 | 76487.3 | 4 | UniProt (P51787) Pfam (PF00520) Pfam (PF07885) Pfam (PF03520) | Homo sapiens (human) | IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1,KQT-like 1,Voltage-gated potassium channel subunit Kv7.1 |
| 2 | B, D, F, H (B, D, F, H) | Calmodulin-3 | polymer | 177 | 19615.4 | 4 | UniProt (P0DP25) Pfam (PF13499) | Homo sapiens (human) | |
| 3 | I, J, K, L (A) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 4 | M, O, Q, S (A, C, E, G) | (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide | non-polymer | 471.6 | 4 | Chemie (I0S) | |||
| 5 | N, P, R, T (B, D, F, H) | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 4 | Chemie (PIO) |
Sequence modifications
A, C, E, G: 1 - 676 (UniProt: P51787)
B, D, F, H: 1 - 149 (UniProt: P0DP25)
| PDB | External Database | Details |
|---|---|---|
| Leu 677 | - | expression tag |
| Glu 678 | - | expression tag |
| Gly 679 | - | expression tag |
| Gly 680 | - | expression tag |
| Ser 681 | - | expression tag |
| Ser 682 | - | expression tag |
| Gly 683 | - | expression tag |
| Gly 684 | - | expression tag |
| Trp 685 | - | expression tag |
| Ser 686 | - | expression tag |
| His 687 | - | expression tag |
| Pro 688 | - | expression tag |
| Gln 689 | - | expression tag |
| Phe 690 | - | expression tag |
| Glu 691 | - | expression tag |
| Lys 692 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 150 | - | expression tag |
| Glu 151 | - | expression tag |
| Gly 152 | - | expression tag |
| Gly 153 | - | expression tag |
| Ser 154 | - | expression tag |
| Ser 155 | - | expression tag |
| Gly 156 | - | expression tag |
| Gly 157 | - | expression tag |
| Leu 158 | - | expression tag |
| Val 159 | - | expression tag |
| Pro 160 | - | expression tag |
| Arg 161 | - | expression tag |
| Gly 162 | - | expression tag |
| Ser 163 | - | expression tag |
| Gly 164 | - | expression tag |
| Gly 165 | - | expression tag |
| Ser 166 | - | expression tag |
| Ser 167 | - | expression tag |
| Gly 168 | - | expression tag |
| Gly 169 | - | expression tag |
| His 170 | - | expression tag |
| His 171 | - | expression tag |
| His 172 | - | expression tag |
| His 173 | - | expression tag |
| His 174 | - | expression tag |
| His 175 | - | expression tag |
| His 176 | - | expression tag |
| His 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 384411.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5029.0 | |
| All* | Total formula weight | 389440.0 |
