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7XN1

Crystal structure of human acetylcholinesterase in complex with tacrine

Replaces:  7E3I
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Acetylcholinesterasepolymer54059232.92UniProt (P22303)
Pfam (PF00135)
Homo sapiens (human)AChE
2C
(C)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched570.51In PDB
GlyTouCan (G21290RB)
3D
(D)
alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched367.31In PDB
GlyTouCan (G86851RC)
4E, G
(A, B)
TACRINEnon-polymer198.32Chemie (THA)
5F
(A)
3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOLnon-polymer370.41Chemie (PE8)
6H, I
(A, B)
waterwater18.033Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight118465.7
BranchedNumber of molecules2
Total formula weight937.9
Non-Polymers*Number of molecules3
Total formula weight767.0
All*Total formula weight120170.6
*Water molecules are not included.

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PDB entries from 2025-07-02

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