7XM3
Crystal structure of Keap1 Kelch domain (residues 322-609) in complex with 6k
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kelch-like ECH-associated protein 1 | polymer | 292 | 31936.6 | 1 | UniProt (Q14145) Pfam (PF01344) | Homo sapiens (human) | Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19 |
| 2 | B (A) | N-[4-[(2-azanyl-2-oxidanylidene-ethyl)-[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]sulfamoyl]phenyl]-3-(4-ethylpiperazin-1-yl)propanamide | non-polymer | 765.9 | 1 | Chemie (GED) |
Sequence modifications
A: 321 - 609 (UniProt: Q14145)
| PDB | External Database | Details |
|---|---|---|
| Gly 318 | - | expression tag |
| Ser 319 | - | expression tag |
| His 320 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31936.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 765.9 | |
| All* | Total formula weight | 32702.5 |
