7XJ0

Structure of human TRPV3 in complex with Trpvicin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, C, A, D	Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP	polymer	1061	120835.4	4	UniProt (B2KYM6) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520) UniProt (by SIFTS) (Q8NET8) In PDB	Homo sapiens (human)
2	D, B, C, A	[(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate	non-polymer		718.0	20	Chemie (6OU)
3	B, C, A, D	N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide	non-polymer		478.4	4	Chemie (EQK)

Sequence modifications

B, C, A, D: 1 - 791 (UniProt: B2KYM6)

PDB	External Database	Details
Ile 25	Val 25	conflict
Arg 117	Gly 117	conflict
Lys 246	Arg 246	conflict
Gly 247	Glu 247	conflict
Asn 772	Asp 772	conflict

B, C, A, D: 792 - 1061 (PDB: 7XJ0)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	483341.5
Non-Polymers*	Number of molecules	24
	Total formula weight	16273.7
All*	Total formula weight	499615.2

*Water molecules are not included.