7XIS
Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with nitrofuran methoxy(methoxycarbonyl)phenyl ester
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Reverse Transcriptase RNase H domain | polymer | 151 | 16832.3 | 1 | UniProt (A0A059PIR4) UniProt (A0A7L9QW77) Pfam (PF00075) UniProt (by SIFTS) (P04585) In PDB | Human immunodeficiency virus 1 | |
2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
3 | A | (2-methoxy-4-methoxycarbonyl-phenyl) 5-nitrofuran-2-carboxylate | non-polymer | 321.2 | 1 | Chemie (E58) | |||
4 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
5 | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A: 7 - 86 (UniProt: A0A059PIR4)
A: 106 - 151 (UniProt: A0A7L9QW77)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
Pro 2 | - | expression tag |
Gly 3 | - | expression tag |
Gly 4 | - | expression tag |
Ser 5 | - | expression tag |
Met 6 | - | expression tag |
Thr 87 | - | linker |
Gln 88 | - | linker |
Trp 89 | - | linker |
Ile 90 | - | linker |
His 91 | - | linker |
Asn 92 | - | linker |
Trp 93 | - | linker |
Lys 94 | - | linker |
Lys 95 | - | linker |
Arg 96 | - | linker |
Gly 97 | - | linker |
Trp 98 | - | linker |
Lys 99 | - | linker |
Thr 100 | - | linker |
Pro 101 | - | linker |
Val 102 | - | linker |
Lys 103 | - | linker |
Asn 104 | - | linker |
Val 105 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 16832.3 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 561.9 | |
All* | Total formula weight | 17394.2 |