7XI4

Crystal Structure of the NPAS4-ARNT heterodimer in complex with DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Aryl hydrocarbon receptor nuclear translocator	polymer	383	43306.2	1	UniProt (P53762) Pfam (PF00010) Pfam (PF00989) Pfam (PF14598) In PDB	Mus musculus (house mouse)	ARNT protein,Dioxin receptor,nuclear translocator,Hypoxia-inducible factor 1-beta,HIF-1-beta,HIF1-beta
2	B	Neuronal PAS domain protein 4	polymer	356	39381.8	1	UniProt (A1L327) Pfam (PF08447) UniProt (by SIFTS) (Q8BGD7) In PDB	Mus musculus (house mouse)
3	C	DNA (5'-D(*GP*GP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*TP*GP*AP*T)-3')	polymer	16	5034.3	1		Mus musculus
4	D	DNA (5'-D(P*CP*CP*AP*TP*CP*AP*CP*TP*CP*AP*CP*GP*AP*CP*CP*T)-3')	polymer	16	4763.1	1		Mus musculus

Sequence modifications

B: 1 - 348 (UniProt: A1L327)

PDB	External Database	Details
Leu 349	-	expression tag
Glu 350	-	expression tag
His 351	-	expression tag
His 352	-	expression tag
His 353	-	expression tag
His 354	-	expression tag
His 355	-	expression tag
His 356	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	92485.4
All*	Total formula weight	92485.4

*Water molecules are not included.