7XHH

High-resolution X-ray cocrystal structure of USP7 in complex with X4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ubiquitin carboxyl-terminal hydrolase 7	polymer	348	40261.5	2	UniProt (Q93009) Pfam (PF00443)	Homo sapiens (human)	Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7
2	C, D (A, B)	3-[4-(aminomethyl)phenyl]-6-[[1-[[2-chloranyl-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]-4-oxidanyl-piperidin-4-yl]methyl]-2-methyl-pyrazolo[4,3-d]pyrimidin-7-one	non-polymer		561.0	2	Chemie (DYO)
3	E, F (A, B)	water	water		18.0	136	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	80523.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1122.1
All*	Total formula weight	81645.1

*Water molecules are not included.