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7XGJ

Crystal structure of human MMP-2 catalytic domain in complex with inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Matrix metalloproteinase-2polymer16818809.93Pfam (PF00413)
UniProt (by SIFTS) (P08253)
Homo sapiens
2D, E, F
(D, E, F)
GZS-ASN-ASP-ALA-LEU-IML-EOE-NH2polymer8985.13synthetic construct
3G, H, M, N, R...
(A, B, C)
ZINC IONnon-polymer65.46Chemie (ZN)
4I, J, K, L, O...
(A, B, C)
CALCIUM IONnon-polymer40.19Chemie (CA)
5V, W, X, Y, Z
(A, B, C, D, E)
waterwater18.038Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight59385.1
Non-Polymers*Number of molecules15
Total formula weight753.2
All*Total formula weight60138.2
*Water molecules are not included.

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PDB entries from 2025-07-16

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