7XGG
Crystal structure of BCL-xL in complex with computationally designed inhibitor protein
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, F, C, E | Bcl-2-like protein 1 | polymer | 172 | 19827.2 | 4 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | Homo sapiens (human) | Bcl2-L-1,Apoptosis regulator Bcl-X |
2 | A, D | BCL-xL and MCL-1 dual inhibitor | polymer | 164 | 18600.2 | 2 | synthetic construct | ||
3 | water | water | 18.0 | 536 | Chemie (HOH) |
Sequence modifications
B, F, C, E: 4 - 47 (UniProt: Q07817)
B, F, C, E: 48 - 172 (UniProt: Q07817)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
His 2 | - | expression tag |
Mse 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 116509.2 | |
All* | Total formula weight | 116509.2 |