7XFG

NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Histone acetyltransferase p300	polymer	102	11081.9	1	UniProt (Q09472) Pfam (PF02135) In PDB	Homo sapiens (human)	p300 HAT,E1A-associated protein p300,Histone butyryltransferase p300,Histone crotonyltransferase p300,Protein 2-hydroxyisobutyryltransferase p300,Protein lactyltransferas p300,Protein propionyltransferase p300
2	B	NUT family member 1	polymer	16	1785.0	1	UniProt (Q86Y26) In PDB	Homo sapiens	Nuclear protein in testis
3	A	ZINC ION	non-polymer		65.4	3	Chemie (ZN)

Sequence modifications

A: 5 - 94 (UniProt: Q09472)

PDB	External Database	Details
Ser 1	-	expression tag
Gly 2	-	expression tag
Gly 3	-	expression tag
Arg 4	-	expression tag
Ala 20	Cys 1738	engineered mutation
Ala 28	Cys 1746	engineered mutation
Ala 71	Cys 1789	engineered mutation
Ala 72	Cys 1790	engineered mutation
Gly 95	-	expression tag
Ser 96	-	expression tag
Glu 97	-	expression tag
Phe 98	-	expression tag
Pro 99	-	expression tag
Ala 100	-	expression tag
Gly 101	-	expression tag
Asn 102	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	12867.0
Non-Polymers*	Number of molecules	3
	Total formula weight	196.2
All*	Total formula weight	13063.2

*Water molecules are not included.