7XFG
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone acetyltransferase p300 | polymer | 102 | 11081.9 | 1 | UniProt (Q09472) Pfam (PF02135) | Homo sapiens (human) | p300 HAT,E1A-associated protein p300,Histone butyryltransferase p300,Histone crotonyltransferase p300,Protein 2-hydroxyisobutyryltransferase p300,Protein lactyltransferas p300,Protein propionyltransferase p300 |
| 2 | B (B) | NUT family member 1 | polymer | 16 | 1785.0 | 1 | UniProt (Q86Y26) | Homo sapiens | Nuclear protein in testis |
| 3 | C, D, E (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
A: 5 - 94 (UniProt: Q09472)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Arg 4 | - | expression tag |
| Ala 20 | Cys 1738 | engineered mutation |
| Ala 28 | Cys 1746 | engineered mutation |
| Ala 71 | Cys 1789 | engineered mutation |
| Ala 72 | Cys 1790 | engineered mutation |
| Gly 95 | - | expression tag |
| Ser 96 | - | expression tag |
| Glu 97 | - | expression tag |
| Phe 98 | - | expression tag |
| Pro 99 | - | expression tag |
| Ala 100 | - | expression tag |
| Gly 101 | - | expression tag |
| Asn 102 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 12867.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 13063.2 |
