7XEZ
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone acetyltransferase p300,NUT family member 1 | polymer | 163 | 17374.0 | 1 | UniProt (Q09472) UniProt (Q86Y26) Pfam (PF02135) | Homo sapiens (human) | p300 HAT,E1A-associated protein p300,Histone butyryltransferase p300,Histone crotonyltransferase p300,Protein 2-hydroxyisobutyryltransferase p300,Protein lactyltransferas p300,Protein propionyltransferase p300,Nuclear protein in testis |
| 2 | B, C, D (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
A: 5 - 94 (UniProt: Q09472)
A: 112 - 163 (UniProt: Q86Y26)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Arg 4 | - | expression tag |
| Ala 20 | Cys 1738 | engineered mutation |
| Ala 28 | Cys 1746 | engineered mutation |
| Ala 71 | Cys 1789 | engineered mutation |
| Ala 72 | Cys 1790 | engineered mutation |
| Gly 95 | - | linker |
| Ser 96 | - | linker |
| Gly 97 | - | linker |
| Gly 98 | - | linker |
| Ser 99 | - | linker |
| Gly 100 | - | linker |
| Gly 101 | - | linker |
| Ser 102 | - | linker |
| Gly 103 | - | linker |
| Gly 104 | - | linker |
| Ser 105 | - | linker |
| Gly 106 | - | linker |
| Gly 107 | - | linker |
| Ser 108 | - | linker |
| Gly 109 | - | linker |
| Gly 110 | - | linker |
| Ser 111 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17374.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 17570.2 |
