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7XE2

Crystal structure of LSD2 in complex with trans-4-Br-PCPA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Lysine-specific histone demethylase 1Bpolymer79389014.62UniProt (Q8NB78)
Pfam (PF07496)
Pfam (PF04433)
Pfam (PF01593)
Homo sapiens (human)Flavin-containing amine oxidase domain-containing protein 1,Lysine-specific histone demethylase 2
2C, D, E, P, Q...
(A, B)
ZINC IONnon-polymer65.46Chemie (ZN)
3F, H, S, U
(A, B)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.54Chemie (FAD)
4G, I, T, V
(A, B)
3-(4-bromophenyl)propanalnon-polymer213.14Chemie (DIJ)
5J
(A)
CITRATE ANIONnon-polymer189.11Chemie (FLC)
6K
(A)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
7L, M, N, O, W
(A, B)
GLYCEROLnon-polymer92.15Chemie (GOL)
8X, Y
(A, B)
waterwater18.0969Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight178029.2
Non-Polymers*Number of molecules21
Total formula weight5186.7
All*Total formula weight183215.9
*Water molecules are not included.

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PDB entries from 2026-02-04

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