7XDL
Cryo-EM structure of SARS-CoV-2 Delta Spike protein in complex with BA7208 and BA7125 fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Spike glycoprotein | polymer | 1116 | 123251.6 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
2 | D, F, H | BA7125 fab | polymer | 211 | 22882.4 | 3 | Homo sapiens | ||
3 | E, G, I | BA7125 fab | polymer | 215 | 22978.7 | 3 | Homo sapiens | ||
4 | J, L, O | BA7208 fab | polymer | 105 | 11515.7 | 3 | Homo sapiens | ||
5 | K, M, P | BA7208 fab | polymer | 120 | 13398.0 | 3 | Homo sapiens | ||
6 | a, N, Q, R, S... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
7 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) |
Sequence modifications
A, B, C: 11 - 1126 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
- | Glu 156 | deletion |
- | Phe 157 | deletion |
Gly 141 | Arg 158 | conflict |
Arg 435 | Leu 452 | conflict |
Lys 461 | Thr 478 | conflict |
Gly 597 | Asp 614 | conflict |
Gly 665 | Arg 682 | conflict |
Ser 666 | Arg 683 | conflict |
Ser 668 | Arg 685 | conflict |
Pro 875 | Ala 892 | conflict |
Pro 882 | Ala 899 | conflict |
Pro 925 | Ala 942 | conflict |
Asn 933 | Asp 950 | conflict |
Pro 969 | Lys 986 | conflict |
Pro 970 | Val 987 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 15 |
Total formula weight | 582079.0 | |
Branched | Number of molecules | 12 |
Total formula weight | 5092.8 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 2654.5 | |
All* | Total formula weight | 589826.3 |