7XDK
Cryo-EM structure of SARS-CoV-2 Delta Spike protein in complex with BA7054 and BA7125 fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, K (A, B, C) | Spike glycoprotein | polymer | 1118 | 123748.2 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 2 | B, G, L (F, K, L) | BA7125 fab | polymer | 214 | 22849.5 | 3 | Homo sapiens | ||
| 3 | C, H, M (G, J, M) | BA7125 fab | polymer | 215 | 23328.9 | 3 | Homo sapiens | ||
| 4 | D, I, N (D, H, N) | BA7054 fab | polymer | 121 | 13146.6 | 3 | Homo sapiens | ||
| 5 | E, J, O (E, I, O) | BA7054 fab | polymer | 107 | 11431.7 | 3 | Homo sapiens | ||
| 6 | AA, P, Q, R, S... (a, P, Q, R, S...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
| 7 | BA, CA, DA, EA, FA... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) |
Sequence modifications
A, B, C: 11 - 1126 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Asp 127 | Gly 142 | conflict |
| Asp 127 | Glu 154 | conflict |
| Met 138 | Ser 155 | conflict |
| Ser 140 | Phe 157 | conflict |
| Gly 141 | Arg 158 | conflict |
| Arg 435 | Leu 452 | conflict |
| Lys 461 | Thr 478 | conflict |
| Asp 513 | Ser 530 | conflict |
| Cys 514 | Thr 531 | conflict |
| Gly 597 | Asp 614 | conflict |
| Asn 933 | Asp 950 | conflict |
| Pro 969 | Lys 986 | conflict |
| Pro 970 | Val 987 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 583514.5 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 5092.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2654.5 | |
| All* | Total formula weight | 591261.8 |
