7XDK
Cryo-EM structure of SARS-CoV-2 Delta Spike protein in complex with BA7054 and BA7125 fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Spike glycoprotein | polymer | 1118 | 123748.2 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
2 | F, K, L | BA7125 fab | polymer | 214 | 22849.5 | 3 | Homo sapiens | ||
3 | G, J, M | BA7125 fab | polymer | 215 | 23328.9 | 3 | Homo sapiens | ||
4 | D, H, N | BA7054 fab | polymer | 121 | 13146.6 | 3 | Homo sapiens | ||
5 | E, I, O | BA7054 fab | polymer | 107 | 11431.7 | 3 | Homo sapiens | ||
6 | a, P, Q, R, S... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
7 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) |
Sequence modifications
A, B, C: 11 - 1126 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Asp 127 | Gly 142 | conflict |
Asp 127 | Glu 154 | conflict |
Met 138 | Ser 155 | conflict |
Ser 140 | Phe 157 | conflict |
Gly 141 | Arg 158 | conflict |
Arg 435 | Leu 452 | conflict |
Lys 461 | Thr 478 | conflict |
Asp 513 | Ser 530 | conflict |
Cys 514 | Thr 531 | conflict |
Gly 597 | Asp 614 | conflict |
Asn 933 | Asp 950 | conflict |
Pro 969 | Lys 986 | conflict |
Pro 970 | Val 987 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 15 |
Total formula weight | 583514.5 | |
Branched | Number of molecules | 12 |
Total formula weight | 5092.8 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 2654.5 | |
All* | Total formula weight | 591261.8 |