7XDG
Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor MDSA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NAD-dependent malic enzyme, mitochondrial | polymer | 584 | 65521.4 | 4 | UniProt (P23368) Pfam (PF00390) Pfam (PF03949) | Homo sapiens (human) | mitochondrial NAD(P)+-dependent malic enzyme,NAD-ME,Malic enzyme 2 |
| 2 | E, F, H, I, K... (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) | |||
| 3 | G, J, M, P (A, B, C, D) | 5-[(3-carboxy-4-oxidanyl-phenyl)methyl]-2-oxidanyl-benzoic acid | non-polymer | 288.3 | 4 | Chemie (D5S) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 262085.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 6460.4 | |
| All* | Total formula weight | 268546.1 |
