7X8Z
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab188
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Spike glycoprotein | polymer | 1278 | 141459.5 | 1 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 2 | B (H) | Ab188 heavy chain | polymer | 265 | 28637.1 | 1 | Severe acute respiratory syndrome coronavirus 2 | ||
| 3 | C (L) | Ab188 light chain | polymer | 248 | 27390.5 | 1 | Severe acute respiratory syndrome coronavirus 2 | ||
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 1 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 682 | Arg 682 | engineered mutation |
| Ser 683 | Arg 683 | engineered mutation |
| Ser 685 | Arg 685 | engineered mutation |
| Pro 817 | Phe 817 | engineered mutation |
| Pro 892 | Ala 892 | engineered mutation |
| Pro 899 | Ala 899 | engineered mutation |
| Pro 942 | Ala 942 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
| Ala 1209 | - | expression tag |
| Ala 1210 | - | expression tag |
| Ala 1211 | - | expression tag |
| Gly 1212 | - | expression tag |
| Ser 1213 | - | expression tag |
| Gly 1214 | - | expression tag |
| Tyr 1215 | - | expression tag |
| Ile 1216 | - | expression tag |
| Pro 1217 | - | expression tag |
| Glu 1218 | - | expression tag |
| Ala 1219 | - | expression tag |
| Pro 1220 | - | expression tag |
| Arg 1221 | - | expression tag |
| Asp 1222 | - | expression tag |
| Gly 1223 | - | expression tag |
| Gln 1224 | - | expression tag |
| Ala 1225 | - | expression tag |
| Tyr 1226 | - | expression tag |
| Val 1227 | - | expression tag |
| Arg 1228 | - | expression tag |
| Lys 1229 | - | expression tag |
| Asp 1230 | - | expression tag |
| Gly 1231 | - | expression tag |
| Glu 1232 | - | expression tag |
| Trp 1233 | - | expression tag |
| Val 1234 | - | expression tag |
| Leu 1235 | - | expression tag |
| Leu 1236 | - | expression tag |
| Ser 1237 | - | expression tag |
| Thr 1238 | - | expression tag |
| Phe 1239 | - | expression tag |
| Leu 1240 | - | expression tag |
| Gly 1241 | - | expression tag |
| Ser 1242 | - | expression tag |
| Ser 1243 | - | expression tag |
| Gly 1244 | - | expression tag |
| Arg 1245 | - | expression tag |
| Glu 1246 | - | expression tag |
| Asn 1247 | - | expression tag |
| Leu 1248 | - | expression tag |
| Tyr 1249 | - | expression tag |
| Phe 1250 | - | expression tag |
| Gln 1251 | - | expression tag |
| Gly 1252 | - | expression tag |
| Gly 1253 | - | expression tag |
| Gly 1254 | - | expression tag |
| Gly 1255 | - | expression tag |
| Ser 1256 | - | expression tag |
| Gly 1257 | - | expression tag |
| Leu 1258 | - | expression tag |
| Asn 1259 | - | expression tag |
| Asp 1260 | - | expression tag |
| Ile 1261 | - | expression tag |
| Phe 1262 | - | expression tag |
| Glu 1263 | - | expression tag |
| Ala 1264 | - | expression tag |
| Gln 1265 | - | expression tag |
| Lys 1266 | - | expression tag |
| Ile 1267 | - | expression tag |
| Glu 1268 | - | expression tag |
| Trp 1269 | - | expression tag |
| His 1270 | - | expression tag |
| Glu 1271 | - | expression tag |
| Gly 1272 | - | expression tag |
| His 1273 | - | expression tag |
| His 1274 | - | expression tag |
| His 1275 | - | expression tag |
| His 1276 | - | expression tag |
| His 1277 | - | expression tag |
| His 1278 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 197487.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 197708.3 |
