7X88
Crystal structure of ENL YEATS domain T2 mutant in complex with histone H3 acetylation at K27
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein ENL | polymer | 155 | 18327.1 | 1 | UniProt (Q03111) Pfam (PF03366) | Homo sapiens (human) | YEATS domain-containing protein 1 |
| 2 | B (B) | Histone H3K27ac(24-27) peptide | polymer | 4 | 487.6 | 1 | UniProt (by SIFTS) (P68431) | Homo sapiens | |
| 3 | C (A) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A: 1 - 146 (UniProt: Q03111)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| - | Pro 112 | deletion |
| - | Pro 113 | deletion |
| Leu 112 | Val 114 | engineered mutation |
| His 147 | - | expression tag |
| His 148 | - | expression tag |
| His 149 | - | expression tag |
| His 150 | - | expression tag |
| His 151 | - | expression tag |
| His 152 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 18814.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 19006.8 |
