7X88

Crystal structure of ENL YEATS domain T2 mutant in complex with histone H3 acetylation at K27

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein ENL	polymer	155	18327.1	1	UniProt (Q03111) Pfam (PF03366) In PDB	Homo sapiens (human)	YEATS domain-containing protein 1
2	B	Histone H3K27ac(24-27) peptide	polymer	4	487.6	1	UniProt (by SIFTS) (P68431) In PDB	Homo sapiens
3	A	CITRIC ACID	non-polymer		192.1	1	Chemie (CIT)
4		water	water		18.0	16	Chemie (HOH)

Sequence modifications

A: 1 - 146 (UniProt: Q03111)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
-	Pro 112	deletion
-	Pro 113	deletion
Leu 112	Val 114	engineered mutation
His 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	18814.6
Non-Polymers*	Number of molecules	1
	Total formula weight	192.1
All*	Total formula weight	19006.8

*Water molecules are not included.