7X79
The crystal structure of human Calpain-1 protease core in complex with 14b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Calpain-1 catalytic subunit | polymer | 714 | 81987.9 | 1 | UniProt (P07384) Pfam (PF00648) Pfam (PF01067) Pfam (PF13833) In PDB | Homo sapiens (human) | Calpain-1 protease core,Calcium-activated neutral proteinase 1,CANP 1,Calpain mu-type,Calpain-1 large subunit,Cell proliferation-inducing gene 30 protein,Micromolar-calpain,muCANP |
| 2 | A | N-[(2S)-3-cyclohexyl-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide | non-polymer | 602.7 | 1 | Chemie (89K) | |||
| 3 | A | HYDROSULFURIC ACID | non-polymer | 34.1 | 1 | Chemie (H2S) | |||
| 4 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 81987.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 717.0 | |
| All* | Total formula weight | 82704.8 |
