7X5E

Nrf2-MafG heterodimer bound with CsMBE1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Transcription factor MafG	polymer	104	12071.9	2	UniProt (O15525) Pfam (PF03131)	Homo sapiens (human)	V-maf musculoaponeurotic fibrosarcoma oncogene homolog G,hMAF
2	B, F (B, F)	Nuclear factor erythroid 2-related factor 2	polymer	113	13255.5	2	UniProt (Q16236) Pfam (PF03131)	Homo sapiens (human)	NF-E2-related factor 2,NFE2-related factor 2,Nrf-2,HEBP1,Nuclear factor,erythroid derived 2,like 2
3	C, G (C, G)	DNA (5'-D(*GP*TP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*TP*CP*AP*T)-3')	polymer	16	4864.2	2		synthetic construct
4	D, H (D, H)	DNA (5'-D(*CP*AP*TP*GP*AP*TP*GP*AP*GP*TP*CP*AP*GP*CP*AP*A)-3')	polymer	16	4931.2	2		synthetic construct
5	I (E)	HEXAETHYLENE GLYCOL	non-polymer		282.3	1	Chemie (P6G)
6	J, K, L, M, N... (A, B, C, D, E...)	water	water		18.0	168	Chemie (HOH)

Sequence modifications

A, E: 21 - 123 (UniProt: O15525)

PDB	External Database	Details
Met 20	-	initiating methionine

B, F: 452 - 560 (UniProt: Q16236)

PDB	External Database	Details
Gly 448	-	expression tag
Pro 449	-	expression tag
His 450	-	expression tag
Met 451	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	70245.4
Non-Polymers*	Number of molecules	1
	Total formula weight	282.3
All*	Total formula weight	70527.8

*Water molecules are not included.