7X13

Structure of IgG-Fc hexamer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Immunoglobulin gamma-1 heavy chain	polymer	245	27568.2	12	UniProt (P0DOX5) Pfam (PF07654)	Homo sapiens (human)	Immunoglobulin gamma-1 heavy chain NIE

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 221 - 441 (UniProt: P0DOX5)

PDB	External Database	Details
Cys 309	Leu 311	conflict
Glu 356	Asp 358	conflict
Met 358	Leu 360	conflict
Asp 442	-	expression tag
Lys 443	-	expression tag
Ser 444	-	expression tag
Thr 445	-	expression tag
Gly 446	-	expression tag
Lys 447	-	expression tag
Pro 448	-	expression tag
Thr 449	-	expression tag
Leu 450	-	expression tag
Tyr 451	-	expression tag
Asn 452	-	expression tag
Val 453	-	expression tag
Ser 454	-	expression tag
Leu 455	-	expression tag
Ile 456	-	expression tag
Met 457	-	expression tag
Ser 458	-	expression tag
Asp 459	-	expression tag
Thr 460	-	expression tag
Gly 461	-	expression tag
Gly 462	-	expression tag
Thr 463	-	expression tag
Cys 464	-	expression tag
Tyr 465	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	330818.3
All*	Total formula weight	330818.3

*Water molecules are not included.