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7X12

Crystal structure of ME1 in complex with NADPH

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
NADP-dependent malic enzymepolymer57264223.44UniProt (P48163)
Pfam (PF00390)
Pfam (PF03949)
Homo sapiens (human)NADP-ME,Malic enzyme 1
2E, G, I, K
(A, B, C, D)
MANGANESE (II) IONnon-polymer54.94Chemie (MN)
3F, H, J, L
(A, B, C, D)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.44Chemie (NDP)
4M, N, O, P
(A, B, C, D)
waterwater18.0485Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight256893.5
Non-Polymers*Number of molecules8
Total formula weight3201.4
All*Total formula weight260095.0
*Water molecules are not included.

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PDB entries from 2025-06-25

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