7X0V
cryo-EM structure of human TRiC-ADP-AlFx
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, I (K, z) | T-complex protein 1 subunit zeta | polymer | 531 | 58106.1 | 2 | UniProt (P40227) Pfam (PF00118) | Homo sapiens (human) | TCP-1-zeta,Acute morphine dependence-related protein 2,CCT-zeta-1,HTR3,Tcp20 |
| 2 | B, J (J, P) | T-complex protein 1 subunit theta | polymer | 548 | 59691.4 | 2 | UniProt (P50990) Pfam (PF00118) | Homo sapiens (human) | TCP-1-theta,CCT-theta,Chaperonin containing T-complex polypeptide 1 subunit 8 |
| 3 | C, K (H, O) | T-complex protein 1 subunit eta | polymer | 543 | 59417.5 | 2 | UniProt (Q99832) Pfam (PF00118) | Homo sapiens (human) | TCP-1-eta,CCT-eta,HIV-1 Nef-interacting protein |
| 4 | D, L (G, N) | T-complex protein 1 subunit gamma | polymer | 545 | 60613.9 | 2 | UniProt (P49368) Pfam (PF00118) | Homo sapiens (human) | TCP-1-gamma,CCT-gamma,hTRiC5 |
| 5 | E, M (E, e) | T-complex protein 1 subunit epsilon | polymer | 539 | 59547.7 | 2 | UniProt (P48643) Pfam (PF00118) | Homo sapiens (human) | TCP-1-epsilon,CCT-epsilon |
| 6 | F, O (I, M) | T-complex protein 1 subunit delta | polymer | 539 | 57996.1 | 2 | UniProt (P50991) Pfam (PF00118) | Homo sapiens (human) | TCP-1-delta,CCT-delta,Stimulator of TAR RNA-binding |
| 7 | G, P (B, L) | T-complex protein 1 subunit beta | polymer | 535 | 57567.1 | 2 | UniProt (P78371) Pfam (PF00118) | Homo sapiens (human) | TCP-1-beta,CCT-beta |
| 8 | H, N (A, a) | T-complex protein 1 subunit alpha | polymer | 556 | 60418.5 | 2 | UniProt (P17987) Pfam (PF00118) | Homo sapiens (human) | TCP-1-alpha,CCT-alpha |
| 9 | AB, CA, DB, FA, GB... (e, E, a, I, M...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 16 | Chemie (ADP) | |||
| 10 | AA, BB, DA, EB, GA... (G, e, E, a, I...) | MAGNESIUM ION | non-polymer | 24.3 | 16 | Chemie (MG) | |||
| 11 | BA, CB, EA, FB, HA... (G, e, E, a, I...) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 16 | Chemie (AF3) | |||
| 12 | AC, BC, MB, NB, OB... (M, L, K, J, H...) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
H, O: 1 - 543 (UniProt: Q99832)
| PDB | External Database | Details |
|---|---|---|
| Ser 290 | Leu 290 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 946716.5 | |
| Non-Polymers* | Number of molecules | 48 |
| Total formula weight | 8567.7 | |
| All* | Total formula weight | 955284.2 |
