7X0V

cryo-EM structure of human TRiC-ADP-AlFx

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	K, z	T-complex protein 1 subunit zeta	polymer	531	58106.1	2	UniProt (P40227) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-zeta,Acute morphine dependence-related protein 2,CCT-zeta-1,HTR3,Tcp20
2	J, P	T-complex protein 1 subunit theta	polymer	548	59691.4	2	UniProt (P50990) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-theta,CCT-theta,Chaperonin containing T-complex polypeptide 1 subunit 8
3	H, O	T-complex protein 1 subunit eta	polymer	543	59417.5	2	UniProt (Q99832) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-eta,CCT-eta,HIV-1 Nef-interacting protein
4	G, N	T-complex protein 1 subunit gamma	polymer	545	60613.9	2	UniProt (P49368) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-gamma,CCT-gamma,hTRiC5
5	E, e	T-complex protein 1 subunit epsilon	polymer	539	59547.7	2	UniProt (P48643) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-epsilon,CCT-epsilon
6	I, M	T-complex protein 1 subunit delta	polymer	539	57996.1	2	UniProt (P50991) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-delta,CCT-delta,Stimulator of TAR RNA-binding
7	B, L	T-complex protein 1 subunit beta	polymer	535	57567.1	2	UniProt (P78371) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-beta,CCT-beta
8	A, a	T-complex protein 1 subunit alpha	polymer	556	60418.5	2	UniProt (P17987) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-alpha,CCT-alpha
9	e, E, a, I, M...	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	16	Chemie (ADP)
10	G, e, E, a, I...	MAGNESIUM ION	non-polymer		24.3	16	Chemie (MG)
11	G, e, E, a, I...	ALUMINUM FLUORIDE	non-polymer		84.0	16	Chemie (AF3)
12		water	water		18.0	16	Chemie (HOH)

Sequence modifications

H, O: 1 - 543 (UniProt: Q99832)

PDB	External Database	Details
Ser 290	Leu 290	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	946716.5
Non-Polymers*	Number of molecules	48
	Total formula weight	8567.7
All*	Total formula weight	955284.2

*Water molecules are not included.