7WZ3
Cryo-EM structure of human TRiC-tubulin-S1 state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | a, A | T-complex protein 1 subunit alpha | polymer | 556 | 60418.5 | 2 | UniProt (P17987) Pfam (PF00118) In PDB | Homo sapiens (human) | TCP-1-alpha,CCT-alpha |
2 | b, B | T-complex protein 1 subunit beta | polymer | 535 | 57567.1 | 2 | UniProt (P78371) Pfam (PF00118) In PDB | Homo sapiens (human) | TCP-1-beta,CCT-beta |
3 | D, d | T-complex protein 1 subunit delta | polymer | 539 | 57996.1 | 2 | UniProt (P50991) Pfam (PF00118) In PDB | Homo sapiens (human) | TCP-1-delta,CCT-delta,Stimulator of TAR RNA-binding |
4 | E, e | T-complex protein 1 subunit epsilon | polymer | 539 | 59547.7 | 2 | UniProt (P48643) Pfam (PF00118) In PDB | Homo sapiens (human) | TCP-1-epsilon,CCT-epsilon |
5 | g, G | T-complex protein 1 subunit gamma | polymer | 545 | 60613.9 | 2 | UniProt (P49368) Pfam (PF00118) In PDB | Homo sapiens (human) | TCP-1-gamma,CCT-gamma,hTRiC5 |
6 | h, H | T-complex protein 1 subunit eta | polymer | 543 | 59417.5 | 2 | UniProt (Q99832) Pfam (PF00118) In PDB | Homo sapiens (human) | TCP-1-eta,CCT-eta,HIV-1 Nef-interacting protein |
7 | Q, q | T-complex protein 1 subunit theta | polymer | 548 | 59691.4 | 2 | UniProt (P50990) Pfam (PF00118) In PDB | Homo sapiens (human) | TCP-1-theta,CCT-theta,Chaperonin containing T-complex polypeptide 1 subunit 8,Renal carcinoma antigen NY-REN-15 |
8 | Z, z | T-complex protein 1 subunit zeta | polymer | 531 | 58106.1 | 2 | UniProt (P40227) Pfam (PF00118) In PDB | Homo sapiens (human) | TCP-1-zeta,Acute morphine dependence-related protein 2,CCT-zeta-1,HTR3,Tcp20 |
9 | g, G, Q, q, Z... | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 6 | Chemie (ADP) |
Sequence modifications
h, H: 1 - 543 (UniProt: Q99832)
PDB | External Database | Details |
---|---|---|
Ser 290 | Leu 290 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 16 |
Total formula weight | 946716.5 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 2563.2 | |
All* | Total formula weight | 949279.7 |