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7WYT

Crystal structures of Na+,K+-ATPase in complex with ouabain

Replaces:  7DDJReplaces:  6KPZ
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, C)
Sodium/potassium-transporting ATPase subunit alpha-1polymer1016112403.92UniProt (P05024)
Pfam (PF00690)
Pfam (PF00122)
Pfam (PF13246)
Pfam (PF00702)
Pfam (PF00689)
Sus scrofa (pig)Na(+)/K(+) ATPase alpha-1 subunit,Sodium pump subunit alpha-1
2B, E
(B, D)
Sodium/potassium-transporting ATPase subunit beta-1polymer30335204.42UniProt (P05027)
Pfam (PF00287)
Sus scrofa (pig)Sodium/potassium-dependent ATPase subunit beta-1
3C, F
(G, E)
FXYD domain-containing ion transport regulatorpolymer657094.12UniProt (Q58K79)
Pfam (PF02038)
Sus scrofa (pig)Na+/K+ ATPase gamma subunit transcript variant a
4G, H, I, J
(F, H, I, J)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.44In PDB
GlyTouCan (G42666HT)
5AA, CA, K, M
(C, A)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
6BA, L
(C, A)
SODIUM IONnon-polymer23.02Chemie (NA)
7DA, EA, LA, N, Z
(C, D, A, G)
CHOLESTEROLnon-polymer386.75Chemie (CLR)
8FA, GA, HA, IA, O...
(C, A)
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINEnon-polymer787.113Chemie (PCW)
9JA, X
(C, A)
OUABAINnon-polymer584.72Chemie (OBN)
10KA, Y
(D, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
11MA, NA
(A, C)
waterwater18.010Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight309404.9
BranchedNumber of molecules4
Total formula weight1697.6
Non-Polymers*Number of molecules28
Total formula weight13920.8
All*Total formula weight325023.3
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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