7WYL

Structure of the EV71 3Cpro with 337 inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	3C protein	polymer	187	20521.5	2	UniProt (E7E815) Pfam (PF00548) In PDB	Enterovirus A71	Protein 3B,Viral protein genome-linked
2	A	N-methyl-N-[[4-(trifluoromethyl)-1,3-thiazol-2-yl]methyl]prop-2-enamide	non-polymer		250.2	1	Chemie (G7L)
3		water	water		18.0	390	Chemie (HOH)

Sequence modifications

A, B: 1 - 183 (UniProt: E7E815)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag
Gly 133	His 133	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	41043.0
Non-Polymers*	Number of molecules	1
	Total formula weight	250.2
All*	Total formula weight	41293.3

*Water molecules are not included.