7WYF
Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) in complex with its inhibitor 50
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 431 | 48946.8 | 1 | UniProt (Q54A96) Pfam (PF01180) UniProt (by SIFTS) (Q08210) In PDB | Plasmodium falciparum (malaria parasite P. falciparum) | |
2 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
3 | A | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
4 | A | ethyl 2-(naphthalen-2-ylamino)-4-oxidanylidene-furan-3-carboxylate | non-polymer | 297.3 | 1 | Chemie (7NE) | |||
5 | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: 158 - 569 (UniProt: Q54A96)
PDB | External Database | Details |
---|---|---|
Met 139 | - | initiating methionine |
Gly 140 | - | expression tag |
His 141 | - | expression tag |
His 142 | - | expression tag |
His 143 | - | expression tag |
His 144 | - | expression tag |
His 145 | - | expression tag |
His 146 | - | expression tag |
Ala 147 | - | expression tag |
Glu 148 | - | expression tag |
Asn 149 | - | expression tag |
Leu 150 | - | expression tag |
Tyr 151 | - | expression tag |
Phe 152 | - | expression tag |
Gln 153 | - | expression tag |
Gly 154 | - | expression tag |
Ala 155 | - | expression tag |
Asp 156 | - | expression tag |
Pro 157 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 48946.8 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 909.7 | |
All* | Total formula weight | 49856.5 |