7WWL

S protein of Delta variant in complex with ZWD12

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Spike glycoprotein	polymer	1271	141102.3	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)	S glycoprotein,E2,Peplomer protein
2	D, F, H (H, I, J)	heavy chain of ZWD12	polymer	123	13731.3	3		Homo sapiens
3	E, G, I (L, M, N)	light chain of ZWD12	polymer	108	11965.3	3		Homo sapiens
4	AA, BA, CA, DA, EA... (a, b, c, d, e...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	23	In PDB GlyTouCan (G42666HT)
5	AB, BB, CB, DB, EB... (C, A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	25	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 1273 (UniProt: P0DTC2)

PDB	External Database	Details
Arg 19	Thr 19	variant
Asp 144	Gly 142	variant
-	Glu 156	deletion
-	Phe 157	deletion
Gly 158	Arg 158	variant
Arg 452	Leu 452	variant
Lys 478	Thr 478	variant
Gly 614	Asp 614	variant
Arg 681	Pro 681	variant
Pro 817	Phe 817	engineered mutation
Pro 892	Ala 892	engineered mutation
Pro 899	Ala 899	engineered mutation
Pro 942	Ala 942	engineered mutation
Asn 950	Asp 950	variant
Pro 986	Lys 986	engineered mutation
Pro 987	Val 987	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	500396.7
Branched	Number of molecules	23
	Total formula weight	9761.2
Non-Polymers*	Number of molecules	25
	Total formula weight	5530.2
All*	Total formula weight	515688.1

*Water molecules are not included.