7WVH

Structure of NAD+ glycohydrolase/Streptolysin O complex from Group A streptococcus

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, B)	NAD+-glycohydrolase	polymer	268	30953.1	2	UniProt (D7S0C0) Pfam (PF07461) UniProt (by SIFTS) (Q9RF14)	Streptococcus pyogenes A20
2	B, C (D, C)	Streptolysin O	polymer	472	52774.0	2	UniProt (P0C0I3) Pfam (PF01289) Pfam (PF17440)	Streptococcus pyogenes A20	SLO,Thiol-activated cytolysin
3	E, F, G, H (A, D, C, B)	water	water		18.0	326	Chemie (HOH)

Sequence modifications

A, B: 193 - 451 (UniProt: D7S0C0)

PDB	External Database	Details
Met 192	-	initiating methionine
Asp 330	Gly 330	engineered mutation
Arg 368	Gly 368	engineered mutation
Leu 452	-	expression tag
Glu 453	-	expression tag
His 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag
His 459	-	expression tag

D, C: 103 - 571 (UniProt: P0C0I3)

PDB	External Database	Details
Met 100	-	initiating methionine
Ala 101	-	expression tag
Ser 102	-	expression tag
Ser 450	Thr 450	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	167454.2
All*	Total formula weight	167454.2

*Water molecules are not included.