7WVE
CT-mut (D523K,D524K,E527K) TLR3-poly(I:C) complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Toll-like receptor 3 | polymer | 680 | 77539.6 | 2 | UniProt (O15455) Pfam (PF13855) Pfam (PF13516) Pfam (PF00560) In PDB | Homo sapiens (human) | |
2 | E | RNA (46-MER) | polymer | 46 | 13993.4 | 1 | synthetic construct | ||
3 | F | RNA (46-MER) | polymer | 46 | 15143.8 | 1 | synthetic construct |
Sequence modifications
A, B: 27 - 697 (UniProt: O15455)
PDB | External Database | Details |
---|---|---|
Ala 24 | - | expression tag |
Asp 25 | - | expression tag |
Pro 26 | - | expression tag |
Lys 523 | Asp 523 | engineered mutation |
Lys 524 | Asp 524 | engineered mutation |
Lys 527 | Glu 527 | engineered mutation |
His 698 | - | expression tag |
His 699 | - | expression tag |
His 700 | - | expression tag |
His 701 | - | expression tag |
His 702 | - | expression tag |
His 703 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 184216.4 | |
All* | Total formula weight | 184216.4 |